- 1890 The Woman's Club of Louisville was organized by Susan Look Avery
- 1890 A memorial was sent to the Constitutional Convention praying that all lottery franchises be repealed
- 1891 Petition presented to the Mayor and City Council asking for matrons in jails and station houses
- 1892 Petition with over 500 signatures presented to retail merchants asking for seats for shop-girls
- 1893 Petition sent to the Kentucky Legislature asking for the age of consent be raised from twelve to eighteen.
- 1893 Petition sent to the Kentucky Legislature asking that the women of Kentucky be granted property rights, the power to make wills and the equal custody of their children.
- 1893 A Free Exhibition of Impressionist paintings was given in which many of the world's most noted artists were represented.
- 1906 The Carnegie Institute declared The Woman's Club of Louisville to be : The greatest ethical influence for public sentiment in the state of Kentucky.
- 1921 The Younger Woman's Club of Louisville was founded.
- 1923 Denishawn Dance Group performs with young dancers Martha Graham (founder of modern dance) and Louise Brooks (Ziegfeld Follies dancer and later iconic silent movie actress with Paramount Pictures.)
- 1932 Fundraiser for the American Foundation for the Blind featuring Helen Keller as speaker.
- 1937 The Woman's Club served as a receiving station for supplies and for flood sufferers.
- 1938 The first No-Jury Art Show was held providing the artists of Louisville a place to exhibit their talent.
- 1939 Poet Robert Frost spoke to Club members and the Community.
- 1941 Community Service Community was formed to help with the war effort, aid children of Appalachia, and provide volunteers to local social services departments, hospitals and charities.
- 1943 Carl Sandberg read some of his work, played the guitar singing rakish ballads.
- 1946 Pianist Lee Luvisi (aged 8) made his first public appearance onstage in the Auditorium.
- 1948 The Louisville Deaf Oral School was founded by The Woman's Club and the Kiwanis.
- 1956 Bookmobiles purchased for the Louisville Free Public Library to provide service to rural communities.
- 1967 The Woman's Club of Louisville Charity Fund, Inc. was established for the purpose of raising and managing funds for charities.
- The Woman's Club of Louisville Charity Fund is a 501(C)3 organization by the IRS. (See recent grants under Charity)